Individual adults represent the largest population of people experiencing homelessness. Ending their homelessness requires innovation and adaptation, especially for those affected by the growing unsheltered crisis. The best approaches will not only focus on increasing housing resources and improving the systemic response, they will also demand an understanding of homelessness through other lenses, including age, gender, race, and health. This will require new partnerships with the systems that are implicated when we examine homelessness through those lenses, especially the health care and criminal justice systems. The Solutions for Individual Homeless Adults conference will explore these emerging perspectives.