Stress is just one of the many hurdles college students face. Short-term stress can help learners raise a grade, polish an essay, or pursue a coveted career opportunity. But long-term stress, if left unaddressed, can have detrimental side effects. According to the American Institute of Stress, 4 in 5 college students experience frequent stress. Unchecked stress can lead to physical side effects like trouble concentrating, irritability, a lack of energy, appetite changes, a weakened immune system, and trouble sleeping.